The role of fibronectin binding protein A (FbpA) in Listeria monocytogenes infection and its pathogenesis were studied in vivo and in vitro by constructing a fbpA-deficient mutant。
The fbpA mutant displayed increased sensitivity to both front-line tuberculosis-targeted drugs as well as other broad-spectrum antibiotics widely used for antibacterial chemotherapy. The。
The fbpA gene encodes a 570-amino-acid polypeptide with strong homologies to the fibronectin-binding proteins PavA of S. pneumoniae, Fbp54 of S. pyogenes and FbpA of S. gordonii. We。
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